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Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease

NCT07376278 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-02-24

No results posted yet for this study

Summary

The goal of this observational study is to identify factors in blood that are associated with response to deep brain stimulation (DBS) surgery in patients with Parkinson's disease. The main questions it aims to answer are:

1. What factors in blood (proteins and RNA) are associated with good vs poor response to DBS?
2. Are these factors able to predict response to DBS?
3. How do these factors change before and after DBS?

Blood and leftover brain tissue (which spontaneously adhere to the surgical instruments) will be taken and routine clinical data (including scores from routine assessments) will be collected from consenting participants who undergo DBS.

Conditions

  • Deep Brain Stimulation
  • PARKINSON DISEASE (Disorder)

Interventions

PROCEDURE

DBS

Deep brain stimulation surgery

Sponsors & Collaborators

  • Queen Elizabeth Hospital, Hong Kong

    collaborator OTHER

  • Hong Kong Center for Neurodegenerative Diseases

    collaborator OTHER

  • Hong Kong University of Science and Technology

    lead OTHER

Principal Investigators

  • Nancy Ip · The Hong Kong University of Science and Technology

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-05
Primary Completion
2036-02-01
Completion
2038-02-01

Countries

  • Hong Kong

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07376278 on ClinicalTrials.gov