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Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome

NCT07366684 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 550

Last updated 2026-05-15

No results posted yet for this study

Summary

This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS). The research includes both a retrospective and a prospective cohort. The aim is to determine whether frailty scores, combined with clinical and laboratory parameters available at admission, can improve risk prediction for complications and mortality compared with standard risk scores (TIMI, GRACE, Syntax). The study will also compare outcomes between patients treated with percutaneous coronary intervention (PCI) and those treated conservatively with medications. Patients will be followed during hospitalization and for six months after discharge. The results are expected to contribute to more personalized treatment strategies for elderly patients with ACS.

Conditions

  • ST Elevation (STEMI) Myocardial Infarction
  • Non ST Elevation Myocardial Infarction (NSTEMI)
  • Unstable Angina Pectoris

Interventions

PROCEDURE

Percutaneous Coronary Intervention (PCI)

Patients receiving PCI as part of routine clinical care

OTHER

Conservative Medical Therapy

Patients treated conservatively with guideline-directed medical therapy as part of routine care

Sponsors & Collaborators

  • University of Nis

    collaborator OTHER

  • Clinical Center Niš

    lead OTHER

Eligibility

Min Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-13
Primary Completion
2027-03-31
Completion
2027-09-30

Countries

  • Serbia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07366684 on ClinicalTrials.gov