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Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI

NCT04034940 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2019-07-30

No results posted yet for this study

Summary

The investigators intend to evaluate Oxidative Stress biomarkers through a. Catalase Activity Assay; b. Lipid Peroxidation Assay; c. SOD Assay; d. Total Antioxidant Capacity Assay; e. Glutathione Peroxidase at patients with acute myocardial infarction STEMI referred for primary PCI; The investigators also aim to evaluate cardiac necrosis by measuring Heart Fatty Acid Binding Protein (H-FABP), TnI, CK, CK-MB, LDH and AST in these patients with acute myocardial infarction referred for primary PCI; Also, the investigators intend to evaluate body composition through bioimpedance spectroscopy (BCM - Fresenius Care) at the moment of admission.

The investigators aim to fully characterise these patients through oxidative millieu, hFABP and make correlations with LVEF dysfunction.

Conditions

  • STEMI
  • Oxidative Stress
  • Oxidative Stress Induction
  • Primary PCI
  • hFABP
  • Left Ventricular Dysfunction
  • BCM

Interventions

OTHER

Dosing Oxidative stress biomarkers & hFABP in STEMI pPCI patients

Dosing oxidative stress biomarkers and hFABP in STEMI pPCI

Sponsors & Collaborators

  • Cardiovascular Diseases Institute IASI, Romania

    collaborator UNKNOWN

  • Grigore T. Popa University of Medicine and Pharmacy

    lead OTHER

Principal Investigators

  • Adrian Covic, Professor · University of Medicine and Pharmacy "Gr. T. Popa" Iasi, Romania

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-31
Primary Completion
2020-07-31
Completion
2020-08-31

Countries

  • Romania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04034940 on ClinicalTrials.gov