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Impact of Different Cardioplegia Solutions on Indicators of Myocardial Injury During Coronary Surgery

NCT07358221 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-01-22

No results posted yet for this study

Summary

The aim of the present study is to investigate intra-operative changes in markers of myocardial injury during ischemia and reperfusion, comparing three methods of myocardial protection; St. Thomas' cold crystalloid cardioplegia, Calafiore warm blood cardioplegia, or modified del Nido cold blood cardioplegia in routine coronary artery bypass grafting procedures.

Conditions

  • Coronary Artery Bypass Grafting (CABG) Surgery
  • Myocardial Protection

Interventions

PROCEDURE

The intervention is the use of a specific cardioplegia solution for myocardial protection

Three different solutions will be used for myocardial protection in this study, and will be compared using markers of myocardial injury

Sponsors & Collaborators

  • Damascus University

    lead OTHER

Principal Investigators

  • Mohammad B Izzat, FRCS(CTh) · Damascus University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-28
Primary Completion
2027-02-28
Completion
2027-02-28

Countries

  • Syria

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07358221 on ClinicalTrials.gov