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Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures

NCT07346742 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 174

Last updated 2026-01-16

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is:

• Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce the occurrence of surgical site infection in children undergoing open groin surgeries?

Researchers will compare no antibiotic use to the use of intravenous prophylactic antibiotics, or antimicrobial-coated sutures to see if the use of intravenous prophylactic antibiotics and antimicrobial-coated sutures significantly reduces the occurrence of surgical site infection following open groin surgeries in children.

Participants will:

* Undergo open groin surgery with either the use of intravenous prophylactic antibiotic or antimicrobial-coated sutures or without antibiotic use
* Visit the clinic on postoperative days 5, 13 and 30 for review of the surgical wounds for any sign of infection.

Conditions

  • Inguinal Hernia
  • Hydroceles
  • Surgical Site Infection

Interventions

DEVICE

Antimicrobial-coated sutures

Use of Antimicrobial-coated sutures to close all layers of the surgical wound following open paediatric groin surgery

DRUG

Intravenous Cefuroxime

Intravenous cefuroxime is given at the induction of anaesthesia

OTHER

Placebo intravenous injection

0.2ml of Vitamin Bco injection + 9.8ml sterile water

Sponsors & Collaborators

  • Olawumi Olajide

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-09
Primary Completion
2026-02-27
Completion
2026-02-27

Countries

  • Nigeria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07346742 on ClinicalTrials.gov