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Worldwide Assessment of Deceased Donor Kidney Utilization

NCT07341516 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 300000

Last updated 2026-01-14

No results posted yet for this study

Summary

The persistent imbalance between kidney transplant demand and organ availability remains a major global challenge. Optimizing the utilization of kidneys from deceased donors is a critical strategy to expand the donor pool and increase access to transplantation. Previous studies have demonstrated substantial international differences in kidney acceptance and discard practices, with significant potential gains in allograft life-years through optimized utilization. However, major changes in allocation policies, donor characteristics, preservation technologies, and global events such as the COVID-19 pandemic may have altered contemporary utilization patterns. This study aims to characterize international trends in deceased donor kidney utilization, compare allograft survival across countries, and estimate potential transplantable allograft life-years gained through improved utilization practices.

Conditions

Sponsors & Collaborators

  • Vanderbilt University Medical Center

    collaborator OTHER

  • Paris Translational Research Center for Organ Transplantation

    lead OTHER

Principal Investigators

  • Alexandre Loupy, MD, PhD · Paris Institute for Transplantation and Organ Regeneration, INSERM, UMR-S970, Paris, France

  • Peter P Reese, MD, PhD · Vanderbilt Center for Transplant Science, Vanderbilt University Medical Center, Nashville, TN, USA

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-01
Primary Completion
2026-11-30
Completion
2026-11-30

Countries

  • United States
  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07341516 on ClinicalTrials.gov