Machine Learning-Based Prediction of Insulin Resistance in Psoriasis Patients Emphasizing Interpretability
NCT07321288 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1265
Last updated 2026-05-08
Summary
Psoriasis is a long-term inflammatory skin disease that can affect overall health. People with psoriasis have a higher risk of developing insulin resistance, a condition in which the body does not respond properly to insulin. Insulin resistance can increase the risk of diabetes, heart disease, and other serious health problems. Because insulin resistance often develops without clear symptoms, many patients are not diagnosed early.
The purpose of this study is to identify which patients with psoriasis are more likely to develop insulin resistance and to create a tool that can help doctors estimate this risk for individual patients. The study will use existing medical records from two medical centers. Researchers will analyze information such as age, body weight, psoriasis severity, blood test results, other medical conditions, and medication history.
Machine learning methods will be used to analyze these data and build a prediction model. The model will be designed to be easy to understand, so doctors can see which factors contribute most to insulin resistance risk.
This study does not involve any new treatments or procedures. All patient information will be anonymized to protect privacy. The results may help doctors identify high-risk patients earlier and support timely monitoring and preventive care.
Conditions
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-01
- Primary Completion
- 2026-09-01
- Completion
- 2026-09-01
Countries
- China
Study Locations
More Related Trials
-
Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases
NCT06387654 ·Status: RECRUITING
-
The Early Detection and Progression of Subclinical Atherosclerosis in Psoriasis
NCT05858099 ·Status: ACTIVE_NOT_RECRUITING
-
Role of CD7 in Skin Inflammation and Psoriasis
NCT00162825 ·Status: COMPLETED
-
Non-invasive Photoacoustic Imaging of Skin Inflammatory Disorders With Machine Learning-assisted Scoring
NCT04809571 ·Status: UNKNOWN ·Phase: NA
-
Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen Planus
NCT06260189 ·Status: RECRUITING
-
The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)
NCT01778569 ·Status: COMPLETED
-
Role of Glucose Metabolism in Migration of Cutaneous Dendritic Cells in Psoriasis
NCT05399433 ·Status: RECRUITING ·Phase: NA
-
Biomarkers of Cancer-Associated Myositis
NCT06808672 ·Status: ACTIVE_NOT_RECRUITING
-
Physiopathological Study and Pharmacological Modulation of Cutaneous Atrophy's Markers Induced by Glucocorticoids
NCT00709579 ·Status: UNKNOWN ·Phase: PHASE3
-
Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.
NCT04904146 ·Status: RECRUITING
-
Evaluation of Aesthetic Impact in Patients With Systemic Sclerosis
NCT03271320 ·Status: COMPLETED
-
Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata
NCT03976622 ·Status: UNKNOWN
-
Cutaneous Microcirculation and Nervous Sensitivity in Psoriasis
NCT02652065 ·Status: COMPLETED ·Phase: NA
-
A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis
NCT03957681 ·Status: COMPLETED ·Phase: PHASE3
-
Cellular and Molecular Biomarkers in Patients With Lichen Planus
NCT06451744 ·Status: RECRUITING ·Phase: NA
-
Assessment of Digital Imaging as a Tool for Diagnosing Psoriasis, Hand Rashes and Unusual Moles
NCT00005781 ·Status: COMPLETED
-
Tissue and Serum Level of NLRP1, NLRP3 and Il-18 in Early Stages of mf Patients
NCT06066554 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Fire Needle Therapy on Plaque Psoriasis With Blood Stasis Syndrome
NCT03953885 ·Status: UNKNOWN ·Phase: NA
-
A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy
NCT00936546 ·Status: COMPLETED ·Phase: PHASE2
-
Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)
NCT03253666 ·Status: COMPLETED
-
Plexin D1 as a Potential Biomarker inPM/DM
NCT05637931 ·Status: UNKNOWN
-
Study of Scaling Disorders and Other Inherited Skin Diseases
NCT00001292 ·Status: COMPLETED
-
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
NCT07021495 ·Status: RECRUITING
-
Molecular Signatures in Inflammatory Skin Disease
NCT03358693 ·Status: RECRUITING
-
Building an Assessment Model for Vitiligo Activity and Prognosis Using Peripheral Blood Cytokine Profiles
NCT07298551 ·Status: NOT_YET_RECRUITING