Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention
NCT07318103 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 153
Last updated 2026-04-09
Summary
Phase II clinical study of HRS-9057 injection in patients with heart failure-induced fluid retention
Conditions
- Fluid Retention Caused by Heart Failure
Interventions
- DRUG
-
HRS-9057 injection set
HRS-9057 injection set
- DRUG
-
5% Glucose Injection or 0.9% sodium chloride injection
5% Glucose Injection or 0.9% sodium chloride injection
Sponsors & Collaborators
-
Fujian Shengdi Pharmaceutical Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-31
- Primary Completion
- 2026-07-31
- Completion
- 2026-08-31
Countries
- China
Study Locations
More Related Trials
-
Effects of Dapagliflozin on Cardiorespiratory Parameters in Heart Failure
NCT05770167 ·Status: UNKNOWN
-
Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity
NCT06820099 ·Status: RECRUITING ·Phase: PHASE2
-
Real-world Comparative Effectiveness and Safety of Jardiance in Chinese Patients With Heart Failure of Reduced Ejection Fraction
NCT07044700 ·Status: NOT_YET_RECRUITING
-
A Dose-finding Study of JMKX003142 in Treatment of Cardiac Edema
NCT06949020 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Dapa Acute Heart Failure Study
NCT05759000 ·Status: RECRUITING
-
Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy
NCT05953831 ·Status: WITHDRAWN ·Phase: PHASE2
-
ERtugliflozin triAl in DIabetes With Preserved or Reduced ejeCtion FrAcTion mEchanistic Evaluation in Heart Failure
NCT03416270 ·Status: COMPLETED ·Phase: PHASE2
-
Real-world Research : Assessment of Effect of Combination of Drugs in the Treatment of Heart Failure
NCT06158711 ·Status: NOT_YET_RECRUITING
-
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
NCT05949801 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy
NCT07021976 ·Status: RECRUITING ·Phase: PHASE3
-
Effect of Dapagliflozin on VT in Patients With Heart Failure.
NCT05550441 ·Status: UNKNOWN ·Phase: PHASE4
-
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
NCT00252187 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy
NCT05879523 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).
NCT00159627 ·Status: COMPLETED ·Phase: PHASE2
-
Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
NCT02653482 ·Status: COMPLETED ·Phase: PHASE4
-
Dapagliflozin in the Treatment of Heart Failure
NCT05727423 ·Status: ACTIVE_NOT_RECRUITING
-
An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
NCT03730961 ·Status: COMPLETED ·Phase: PHASE2
-
Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction
NCT05556044 ·Status: RECRUITING ·Phase: PHASE3
-
A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure
NCT01357850 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With Acute Heart Failure
NCT02135835 ·Status: COMPLETED ·Phase: PHASE4
-
Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure
NCT06552637 ·Status: RECRUITING ·Phase: NA
-
Dose-comparison Study of Prednisone in Heart Failure
NCT01559727 ·Status: COMPLETED ·Phase: PHASE3
-
Metformin in Heart Failure Without Diabetes
NCT03331861 ·Status: TERMINATED ·Phase: PHASE2
-
A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure)
NCT00234104 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of CRD-740 in Heart Failure
NCT05409183 ·Status: TERMINATED ·Phase: PHASE2