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Impact of Interventional Revascularization on the Physiological Assessment of Bystander Coronary Lesions by FFR

NCT07314879 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2026-01-02

No results posted yet for this study

Summary

The ABC-FFR trial examines the understudied hemodynamic interaction between parallel coronary stenoses, as the physiological impact of treating one lesion on the pressure indices of lesions in separate parallel branches is not yet fully understood. This prospective, multicenter study enrolls patients scheduled for percutaneous coronary intervention (PCI) of a designated index lesion who also present with a concurrent remote stenosis in a parallel coronary artery. It evaluates potential changes in fractional flow reserve (FFR) and non-hyperemic pressure ratio (NHPR) measurements within the remote lesion both before and after the index lesion is revascularized.

Conditions

Interventions

DIAGNOSTIC_TEST

Hemodynamic Evaluation of Remote Lesion before & after PCI of Index Lesion

Initial hemodynamic evaluation of the remote, parallel lesion, followed by the planned percutaneous coronary intervention of the index lesion, and a final hemodynamic reevaluation of the remote lesion

Sponsors & Collaborators

  • University of Erlangen-Nürnberg Medical School

    collaborator OTHER

  • University Hospital Erlangen

    collaborator OTHER

  • Friedrich-Alexander-Universität Erlangen-Nürnberg

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-10
Primary Completion
2025-06-26
Completion
2025-06-26

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07314879 on ClinicalTrials.gov