[18F]FES PET/CT for the Detection of Distant Metastasis in Low-grade ER-positive Stage III Breast Cancer
NCT07314073 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 85
Last updated 2026-01-02
Summary
This study aims to evaluate the detection rate of distant metastases using \[18F\]FES PET/CT in patients with low-grade, ER-positive stage III breast cancer.
Conditions
- Stage III Breast Cancer
Interventions
- DIAGNOSTIC_TEST
-
Fluoroestradiol (18F)
Images for 90 minutes after F-18 FES injection
Sponsors & Collaborators
-
Asan Medical Center
lead OTHER
Principal Investigators
-
Hyehyun Jeong · Asan Medical Center
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-24
- Primary Completion
- 2028-12-31
- Completion
- 2029-12-31
Countries
- South Korea
Study Locations
More Related Trials
-
FES (16α-[18F]-Fluoro-17β-estradiol)-PET: Towards a New Standard to Stage Locally Advanced and Recurrent, Estrogen Receptor Positive (ER+) Breast Cancer? Pilot Study to Compare [18F]FES-PET and [18F]FDG-PET
NCT03726931 ·Status: COMPLETED ·Phase: NA
-
[18F]FES PET/CT in Endocrine Refractory Breast Cancer
NCT02409316 ·Status: COMPLETED ·Phase: PHASE2
-
The Value of 18F-FES-PET/CT in Predicting Fulvestrant Efficacy in Breast Cancer
NCT03768479 ·Status: UNKNOWN ·Phase: NA
-
Diagnostic Performance of [18F]FES PET/CT for Axillary LN Metastasis in Invasive Lobular Carcinoma
NCT05960201 ·Status: COMPLETED ·Phase: PHASE2
-
Estrogen Receptor (ER) PET/CT Imaging in Breast Cancer
NCT05541367 ·Status: RECRUITING
-
F-18 FES PET/CT in Measuring Hormone Expression in Patients With Primary, Recurrent, or Metastatic Breast Cancer Undergoing Endocrine-Targeted Therapy
NCT02149173 ·Status: TERMINATED ·Phase: NA
-
18F-fluoroestradiol (FES) PET/CT for Breast Cancer
NCT04883814 ·Status: UNKNOWN ·Phase: PHASE2
-
Correlation of 16α-[18F]Fluoro-17β-estradiol PET Imaging With ESR1 Mutation
NCT03544762 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison Between ER Loss and Triple-Negative Breast Cancer Guided by 18F-FES PET/CT in Metastatic Breast Cancer
NCT07316439 ·Status: ACTIVE_NOT_RECRUITING
-
Test - Retest Reproducibility of 18F Fluoroestradiol (FES) PET
NCT03065712 ·Status: WITHDRAWN ·Phase: PHASE2
-
Positive ER Expression Assessed by 18F-FES PET/CT in the MBC with ER-negative Primary Tumor
NCT06344767 ·Status: COMPLETED
-
Prediction of Response to 2nd-line Hormone Therapy by FES CT/PET in Patients With Metastatic Breast Cancer
NCT03442504 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
NCT06557148 ·Status: RECRUITING
-
Evaluation of the Unconformity of the Hormonal Status of Metastatic Lesions During a First Relapse of Breast Cancer Initially Expressing Estrogen Receptors: a Pilot Study on the Interest of PET With FES
NCT03873428 ·Status: RECRUITING ·Phase: NA
-
16α-18F-fluor-17β-estradiol PET/CT for Visualisation of Estrogen Receptor Positive Liver Metastases From Breast Cancer
NCT04150731 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Use of FES-PET Imaging as a Tool to Detect a Possible Reversion of Estrogen Receptor (ER)-α Status in Patients With Metastatic Breast Cancer HER2 + and ERα Neg Treated With Trastuzumab + Pertuzumab + Taxane.
NCT03619044 ·Status: TERMINATED ·Phase: NA
-
18F-fluoroestradiol (18F-FES) PET/CT Guided First-line Treatment for HR+/HER2- Metastatic Breast Cancer Patients
NCT06655545 ·Status: COMPLETED
-
Serial FES PET/CT to Measure Hormone Expression in Patients Undergoing Endocrine Targeted Therapy
NCT04692103 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
FDG PET-CT in Advanced Breast Cancer
NCT07173868 ·Status: RECRUITING
-
Study to Determine the Utility of FES-PET in the Prediction of Response to Fulvestrant in Women With Estrogen Positive Metastatic Breast Cancer
NCT03507088 ·Status: COMPLETED ·Phase: NA
-
Early Interim 18F-FDG-PET and 18F-FLT-PET for Predicting Treatment Response and Survival in Metastatic Breast Cancer
NCT04411966 ·Status: COMPLETED ·Phase: NA
-
18F FES-PET/MRI for Tailoring Treatment of Luminal a and Lobular Breast Cancer
NCT05982496 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Negative ER Expression Assessed by 18F-FES PET/CT in the MBC With ER-positive Primary Tumor
NCT05797987 ·Status: COMPLETED
-
Impact of 18F-FES PET on the Therapeutic Treatment of Patients With Metastatic Breast Cancer
NCT05486182 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Dynamic and Test-retest Whole Body [18F]FES PET Imaging in Patients With Metastatic ER+ Breast Cancer
NCT05088785 ·Status: RECRUITING ·Phase: NA