Machine Learning and Artificial Intelligence Algorithms to Optimize the Performance and Delivery of Acute Dialysis
NCT07312929 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 7500
Last updated 2026-01-12
Summary
SMART DIALYSIS - Scaling Machine Learning and Artificial Intelligence AlgoRithms to OpTimize the Performance and Delivery of Acute DIALYSIS.
Hypothesis:
Can the investigators develop and implement Machine Learning and Artificial Intelligence Algorithms into Clinical Information Systems to Optimize the Prescription, Delivery, and Performance of Acute Dialysis?
Objective(s):
1. Identify variables surrounding identified Key Performance Indicators that may be used by Machine Learning and Artificial Intelligence algorithms to optimize the prescription and performance of acute dialysis.
2. Develop Machine Learning and Artificial Intelligence algorithms to help guide the prescription and delivery of acute dialysis in the development of Clinical Decision Support tools and Best Practice Advisories and create a ML/AI Augmented SMART DIALYSIS Digital Dashboard.
3. Implement and evaluate the performance of the developed Machine Learning and Artificial Intelligence algorithms on patient-centered and health economic outcomes.
4. Validate and benchmark the performance of the evaluated Machine Learning and Artificial Intelligence algorithms across multiple jurisdictions.
Conditions
- Renal Dialysis
- Renal Replacement Therapy
- Renal Diseases
- Quality Health Care
Interventions
- DEVICE
-
intermittent OR continuous renal replacement therapies
We will include any critically ill patient admitted to an intensive care unit requiring acute dialysis.
Sponsors & Collaborators
-
University of Alberta
lead OTHER
Principal Investigators
-
Oleksa G Rewa, MD MSc · University of Alberta
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-01
- Primary Completion
- 2030-06-30
- Completion
- 2031-06-30
More Related Trials
-
Haemodialysis Outcomes & Patient Empowerment Study 03
NCT05735288 ·Status: COMPLETED
-
High Flux Hemodialysis Thrice Versus Once
NCT00714662 ·Status: UNKNOWN ·Phase: PHASE3
-
Integrated Patient Care Intradialysis Programme in Hemodialysis Through a Virtual Health Platform
NCT04823286 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Green Dialysis: Dialysis With Reduced Dialysate Flow
NCT05974436 ·Status: COMPLETED ·Phase: NA
-
Comparison of Cardiac Index and Cardiac Output Effect During Maintenance Hemodialysis Between Acetate-Free and Acetate-Based Online Hemodiafiltration
NCT01778283 ·Status: COMPLETED ·Phase: PHASE4
-
REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs
NCT02950389 ·Status: COMPLETED ·Phase: NA
-
Impact of Residual Renal Function on Complications in Chronic Hemodialysis Patients
NCT03854513 ·Status: UNKNOWN
-
Online Hemodiafiltration vs Conventional Hemodialysis in Acute Kidney Injury
NCT04525092 ·Status: COMPLETED ·Phase: NA
-
Clinical and Biochemical Effects of Multipass Hemodialysis
NCT01267760 ·Status: COMPLETED ·Phase: PHASE2
-
Protein-bound Uremic Retention Solutes and Long Nocturnal Hemodialysis: a Longitudinal Analysis
NCT00417339 ·Status: COMPLETED
-
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
NCT03874117 ·Status: COMPLETED ·Phase: NA
-
Examining the Impact of Using Two Dialysers in Parallel on Dialysis Adequacy in Hemodialysis Patients
NCT01539252 ·Status: COMPLETED ·Phase: NA
-
A Prospective, Open-label, Multi-center Pilot Study to Evaluate the Safety, Feasibility and Usability of the IDA
NCT05342935 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Conventional Dialysis and the Allient System
NCT00788905 ·Status: UNKNOWN ·Phase: NA
-
RandomizEd ClinicAL triaL on the Efficacy and saFety of Incremental Hemodialysis (REAL-LIFE)
NCT04360694 ·Status: RECRUITING ·Phase: NA
-
Long Term Physical Activity for Hemodialysis Patients
NCT02860312 ·Status: UNKNOWN ·Phase: NA
-
Describe the Effect of the Optimized Hemodialysis Technique (HDx) With Medium Cut-Off Membrane on Recovery Time and Quality of Life
NCT05689801 ·Status: UNKNOWN ·Phase: NA
-
Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy
NCT06425289 ·Status: NOT_YET_RECRUITING
-
Optimisation of Anticoagulation in Patients on Nocturnal Hemodialysis
NCT05204810 ·Status: COMPLETED ·Phase: NA
-
How to Prevent Complications During Dialysis
NCT06962124 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Comparison of Dialysis Strategies in Critically Ill Patients With Acute Renal Failure
NCT00322530 ·Status: COMPLETED ·Phase: NA
-
Impact of Regular Low-Frequency Hemoperfusion on Medium- to Long-Term Prognosis in Maintenance Dialysis Patients
NCT07348913 ·Status: COMPLETED
-
Hemodialysis Health Management Model
NCT05281497 ·Status: COMPLETED ·Phase: NA
-
Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients
NCT07269379 ·Status: RECRUITING ·Phase: NA
-
Ultrafiltration Profiling and Outcomes Among Individuals on Maintenance Hemodialysis
NCT03301740 ·Status: COMPLETED ·Phase: NA