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Impact of Arterial Partial Pressure of Oxygen on Anastomotic Leakage After Esophagectomy

NCT07309991 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2083

Last updated 2025-12-30

No results posted yet for this study

Summary

This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. We conducted a retrospective analysis of cases from our center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.

Conditions

  • Esophageal Carcinoma
  • Esophageal Adenocarcinoma
  • Esophagectomy
  • PaO2
  • Esophageal Anastomotic Leakeage

Sponsors & Collaborators

  • Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Hong Yang, M.D. · Department of Thoracic Surgery, Sun Yat-sen University Cancer Center

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2025-12-01
Completion
2025-12-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07309991 on ClinicalTrials.gov