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Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life

NCT07306468 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2025-12-29

No results posted yet for this study

Summary

This observational study aims to evaluate exercise capacity, pulmonary function, respiratory muscle strength, and quality of life in individuals diagnosed with schizophrenia and bipolar disorder. These psychiatric conditions are associated with sedentary lifestyles, metabolic side effects of psychotropic medications, and increased comorbidity risks, all of which may negatively impact physical fitness and respiratory health. By assessing cardiorespiratory endurance, pulmonary parameters (FVC, FEV₁), and respiratory muscle strength in this population, the study seeks to identify physiological limitations and contribute to the development of more effective rehabilitation strategies. The findings may support multidisciplinary approaches to improving physical health and overall quality of life in individuals with severe mental illness.

Conditions

  • Schizophenia Disorder
  • Bipolar Disorder (BD)

Interventions

OTHER

Pulmonary Function Test

Participants' respiratory functions will assess with pulmonary function test according to ATS/ERS criteria

OTHER

Respiratory Muscle Strength Evaluation

Participants' respiratory muscle strenght will assess with maximal inspiratory pressure and maximal expiratory pressure assessment according to ATS/ERS criteria

OTHER

Quality of Life Assessment

Participants' quality of life will assess with WHOQOL-Bref questionnaire

OTHER

Exercise Capacity Assessment

Participants' exercise capacity will assess with 6 Minute Walk Test according to ATS/ERS criteria

Sponsors & Collaborators

  • Çankırı Karatekin University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-11-01
Primary Completion
2026-11-01
Completion
2026-12-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07306468 on ClinicalTrials.gov