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Pilot Study of Negative Pressure Neck Therapy (NPNT)

NCT07301567 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2025-12-24

No results posted yet for this study

Summary

Obstructive sleep apnea (OSA) is a serious, chronic sleep-related breathing disease in which the upper airway repeatedly collapses during sleep, leading to intermittent oxygen deprivation. This pilot study will evaluate the Safety and Efficacy of Negative Pressure Neck Therapy (NPNT) in up to 10 healthy participants. Participants will undergo 2 separate home sleep apnea tests (HSAT) approximately 1 week apart and will be randomly assigned to wear the NPNT device at either night 1 or night 2 of HSAT. Participation will include 5 on-site visits and 1 phone call over approximately 1 month.

Conditions

  • Obstructive Apnea
  • Sleep Apnea Syndrome, Obstructive
  • Sleep Disorder (Disorder)

Interventions

DEVICE

Negative Pressure Neck Therapy (NPNT)

Negative pressure neck therapy (NPNT) is a self-contained, non-invasive, soft, flexible, external neck collar

Sponsors & Collaborators

  • Vancouver Coastal Health Research Institute

    collaborator OTHER

  • University of British Columbia

    lead OTHER

Principal Investigators

  • John A Fleetham, MD · VCHA/UBC

Study Design

Allocation
RANDOMIZED
Purpose
DEVICE_FEASIBILITY
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07301567 on ClinicalTrials.gov