Extended-field Proton Therapy for Cervical Cancer
NCT07298642 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 44
Last updated 2025-12-23
Summary
Severe lymphopenia is a common complication of extended-field radiotherapy in cervical cancer, significantly impacting immune function and clinical outcomes. This study aims to evaluate whether proton therapy, with its superior dose distribution, can reduce lymphopenia and improve survival and toxicity profiles compared to photon therapy.
Conditions
Interventions
- RADIATION
-
Proton extended field radiation therapy
Proton extended field radiation therapy
- RADIATION
-
Photon extended field radiation therapy
Photon extended field radiation therapy
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 85 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-30
- Primary Completion
- 2030-05-31
- Completion
- 2030-05-31
Countries
- Taiwan
Study Locations
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