TCM as an Adjuvant Treatment in Mycobacterium Abscessus Pulmonary Disease

Summary

Chinese herbs can facilitate sputum culture conversion, promote lesion absorption, and enhance clinical symptoms and quality of life for patients with Mycobacterium abscessus pulmonary disease (MAB-PD). The investigators aimed to evaluate the efficacy of Chinese herbs as adjunct therapy to improve cure rates or reduce recurrence rates during the continuation phase of MAB-PD treatment.

Conditions

• Mycobacterium Abscessus Pulmonary Disease

Interventions

DRUG

Chinese herbs-I

This is an empirical traditional Chinese medicine compound used in the treatment of Mycobacterium abscessus pulmonary disease for a long time

DRUG

Chinese herbs-I placebo

Chinese herbs-I placebo

DRUG

Chinese herbs-II

This is an empirical traditional Chinese medicine compound used in the treatment of Mycobacterium abscessus pulmonary disease during the continuation phase for a long time

DRUG

Chinese herbs-II placebo

Chinese herbs-II placebo

Sponsors & Collaborators

• Shanghai Pulmonary Hospital, Shanghai, China

  collaborator OTHER

• Anhui Chest Hospital

  collaborator OTHER

• Guangzhou Chest Hospital.

  collaborator UNKNOWN

• Jiangxi Chest Hospital

  collaborator UNKNOWN

• Beijing Chest Hospital

  collaborator OTHER

• China-Japan Friendship Hospital

  collaborator OTHER

• Huashan Hospital

  collaborator OTHER

• Shanghai University of Traditional Chinese Medicine

  lead OTHER

Principal Investigators

• Zhenhui Lu · Longhua Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-09-08

Primary Completion

2028-11-30

Completion

2028-11-30

Countries

• China

Study Locations