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Pleth Variability Index as a Predictor for Post-induction Hypotension in Elderly Patients

NCT04886089 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 85

Last updated 2025-04-08

No results posted yet for this study

Summary

Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension

Conditions

  • Post-induction Hypotension

Interventions

DEVICE

Pleth variability index for prediction of post-induction hypotension

The use of the baseline Pleth variability index values for prediction of occurrence of post-induction hypotension

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Eligibility

Min Age
65 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-01
Primary Completion
2023-08-01
Completion
2025-01-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04886089 on ClinicalTrials.gov