Do Topical Antibiotics Improve Skin Graft Results?

NCT07286851 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 142

Last updated 2025-12-16

No results posted yet for this study

Summary

The goal of this study is to see if putting antibiotic ointment on a skin graft when the surgery is being done helps prevent the skin graft from getting infected after the operation. The study is looking at all skin grafts done in a rural Bangladesh hospital.

The main questions it aims to answer are:

Does the antibiotic lower the number of infections that happen? Does the antibiotic make the overall outcome of the skin graft better? Do patients who get the antibiotic need fewer extra surgeries?

Researchers will compare the outcomes from patients who had skin grafts before the hospital started applying antibiotic ointment to the outcomes of patients after the hospital began applying antibiotic ointment.

Participants who have already had their skin graft treatment completed will have their medical records reviewed by researchers. The outcomes of their treatment will be written down.

Conditions

  • Skin Transplantation
  • Wounds and Injuries
  • Antibiotic Prophylaxis Surgery

Interventions

DRUG

Neomycin

Topical neomycin was applied at the time of split-thickness skin graft surgery.

Sponsors & Collaborators

  • LAMB Project

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2025-08-31
Completion
2025-08-31

Countries

  • Bangladesh

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07286851 on ClinicalTrials.gov