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Predictors of rTMS and Group Therapy Efficacy in Adolescent Depression

NCT07283419 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 163

Last updated 2025-12-15

No results posted yet for this study

Summary

This study aims to identify baseline predictors of treatment efficacy in adolescents with Major Depressive Disorder (MDD) undergoing a combined intervention of repetitive transcranial magnetic stimulation (rTMS) and group therapy. Specifically, the study investigates the predictive value of family environment characteristics (cohesion, conflict, expressiveness) and cognitive functions (executive function, attention/inhibition).

Conditions

  • Major Depressive Disorder (MDD)
  • Adolescent Depression

Interventions

DEVICE

Repetitive Transcranial Magnetic Stimulation (rTMS)

High-frequency (10 Hz) rTMS applied over the left dorsolateral prefrontal cortex (DLPFC), administered 5 days per week for 4 weeks (20 sessions total).

BEHAVIORAL

Group Cognitive Behavioral Therapy (CBT)

Manualized group therapy sessions focused on psychoeducation, cognitive restructuring, emotion regulation, and interpersonal skills, held twice weekly for 4 weeks (8 sessions total).

Sponsors & Collaborators

  • The First Hospital of Hebei Medical University

    lead OTHER

Eligibility

Min Age
12 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-01
Primary Completion
2024-07-31
Completion
2024-07-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07283419 on ClinicalTrials.gov