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Effect of Exercise on Ultrasound SWV in CTS Patients

NCT07281573 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 91

Last updated 2025-12-22

No results posted yet for this study

Summary

Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy, and studies suggest exercises can be used for symptom management. Purpose: The study evaluated the impact of exercise protocols on the ultrasound shear wave velocity (SWV) of the median nerve and 3rd flexor digitorum superficialis (3rd FDS) in participants with mild to moderate CTS. Methods: Ninety-one CTS participants (79 females) were divided into control group, nerve and tendon gliding exercise group, and strength exercise group. The participants followed a three-week daily exercise plan. The SWV measurements were conducted using Canon Aplio i800 ultrasound and linear probe (LX18i5). Regions of interest were positioned within the nerve epineurium and hyperechogenic borders of the 3rd FDS tendon. The pre- and post-intervention SWV values were recorded. Results: In preliminary results on a smaller sample, trends indicated reduced SWV in both the median nerve and 3rd FDS in the nerve and tendon gliding group and reduced SWV in the median nerve in the strengthening group. No measurable change was observed in the 3rd FDS in strength group and in the control group. Conclusion: Trends suggest specific exercises may decrease stiffness in the median nerve and 3rd FDS in CTS participants.

Conditions

  • Carpal Tunnel Syndrome
  • Peripheral Neuropathies

Interventions

OTHER

Nerve and tendon gliding exercises and strength exercises

The intervention lasted for 3 weeks and was performed once daily. Each participant recieved a detailed exercise plan including sets and repetitions and exercise description in steps and images of body parts position at each step of the exercise. The first session was demonstrated and supervised by a kinesiologist with 8 years of experiences. Nerve and tendon gliding exercises included the movements of arms, hands palms and fingers that triggered the gliding of the median nerve and 3rd FDS tendon through the carpal tunnel. There were 5 exercises for nerve gliding and 5 exercises for tendon gliding in the exercise plan. Furthermore the strength group exercise plan also included 5 exercises that were focusing on fingers and palm flexion and extension with therapeutic ball and elastic bands and wrist flexion and extension using low weight dumbbells (\<2.0kg).

Sponsors & Collaborators

  • University Medical Centre Ljubljana

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-07
Primary Completion
2025-07-14
Completion
2025-10-21

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07281573 on ClinicalTrials.gov