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Molecular Evaluation of TAAR1 and JAK/STAT Pathway in Hidradenitis Suppurativa

NCT07278011 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2025-12-11

No results posted yet for this study

Summary

This observational translational study aims to investigate gene and protein expression in lesional and perilesional skin of patients with Hidradenitis Suppurativa (HS) compared to controls. Skin biopsies were collected from 15 HS patients and 15 age- and sex-matched healthy controls. Gene expression of 15 selected proteins was analyzed using qRT-PCR, while protein levels of 4 targets were assessed by Western blot. The study seeks to identify molecular pathways involved in HS pathogenesis and potential biomarkers for disease severity.

Conditions

  • Hidradenitis Suppurativa (HS)
  • Skin Inflammation

Sponsors & Collaborators

  • Trakya University

    lead OTHER

Principal Investigators

  • Yıldız Gürsel Ürün, MD · Trakya University

  • Zeynep Banu Doğanlar, PhD · Trakya University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-06
Primary Completion
2025-09-25
Completion
2025-11-21

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07278011 on ClinicalTrials.gov