Betamethasone Phonophoresis For Vitiligo
NCT07267273 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-12-05
Summary
Vitiligo is a skin disorder that results in the formation of depigmented patches or hypopigmented macules due to selective destruction or reduction of melanocytes the cells that produce pigment in our skin.
Vitiligo affects 0.1-2% of the World's population. People of all skin types and all ages can be affecte. In most of the cases, white patches develop or expand slowly overtime, and in some cases it never progress and remains stable . Vitiligo can be segmental or non-segmental depending upon the morphology of the clinical involvement. It can also be classified as stable or unstable based on the activity of disease.
Steroids act as anti-inflammatory and immunosuppressant agents. Even if different classes of steroids are now available, the mid- potent ones (e.g. betamethasone dipropionate 0.05% cream, 0.05% clobetasol propionate ointment) are usually preferred for the treatment of young patients .
Now days, topical corticosteroids are the most commonly prescribed agents in treatment of dermatologic conditions .Almost all treatments of vitiligo have borrowed from therapies whose prime targets have been another disease.
Conditions
- Vitiligo
Interventions
- DRUG
-
Beclomethasone
to determine the effect of betamethasone phonophoresis on vitiligo patients.
Sponsors & Collaborators
-
Cairo University
lead OTHER
Principal Investigators
-
Nisreen Afify Abd-Elrasheed, Professor · Physical Therapy for Surgery,Faculty of Physical Therapy,Cairo University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 25 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-10
- Primary Completion
- 2026-02-01
- Completion
- 2026-02-10
Countries
- Egypt
Study Locations
More Related Trials
-
Effects of Combination Therapy With Camouflage in the Repigmentation of Vitiligo
NCT03973073 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo
NCT04765826 ·Status: UNKNOWN ·Phase: NA
-
Contribution of Skin Color in Stabilization of Active Cases of Vitiligo by Narrow Band UVB
NCT04030988 ·Status: UNKNOWN ·Phase: PHASE1
-
Treatment of Acral Vitiligo : Narrowband Ultraviolet-B and Microneedling With and Without Platelet Rich Plasma
NCT03155698 ·Status: UNKNOWN ·Phase: NA
-
Oral Ginkgo Biloba and Narrow Band UVB in the Treatment of Vitiligo
NCT01006421 ·Status: UNKNOWN
-
Effect Of Topical Prostaglandin F2α Analogs,Fractional CO2 Laser, Excimer Laser Or Their Combination In Treatment Of Vitiligo
NCT04577027 ·Status: UNKNOWN ·Phase: PHASE4
-
Fractional Carbon Dioxide Laser,Topical Corticosteroid and Narrow Band Ultraviolet B in Treatment of Stable Vitiligo
NCT03158675 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo
NCT01333410 ·Status: UNKNOWN ·Phase: PHASE4
-
Ginkgo Biloba for the Treatment of Vitiligo Vulgaris in Adolescents
NCT00907062 ·Status: COMPLETED ·Phase: PHASE1
-
Latanoprost Plus NB-UVB Versus Each Alone in Non-segmental Vitiligo: Clinical and Laboratory Evaluation
NCT04811326 ·Status: UNKNOWN ·Phase: PHASE4
-
5-fluorouracil for Treatment of Stable Vitiligo
NCT06209138 ·Status: COMPLETED ·Phase: NA
-
Comparing the Therapeutic Efficacy of Pimecrolimus Cream With Betamethasone Cream for Discoid Lupus Erythematosus
NCT00608673 ·Status: COMPLETED ·Phase: NA
-
Combined Therapy With Narrow-Band Ultraviolet B Phototherapy and Apremilast for the Treatment of Vitiligo
NCT03123016 ·Status: COMPLETED ·Phase: PHASE2
-
Diphenylcyclopropenone (DPCP) as a Depigmenting Therapy in Extensive Vitiligo
NCT04775979 ·Status: COMPLETED ·Phase: PHASE4
-
Methotrexate Iontophoresis Versus Methotrexate 1% Gel on Depigmentation in Vitiligo Patients
NCT07208890 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Assessing the Efficacy of Needling With or Without Corticosteroids in the Repigmentation of Vitiligo
NCT02191748 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Improved Phototherapy in Patients With Vitiligo
NCT05836441 ·Status: UNKNOWN ·Phase: NA
-
Phototherapy Combination With Topicals in Vitiligo
NCT04440371 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Efficacy of Microneedling and Topical Methotrexate Versus Microneedling and Topical 5-flourouracil in Treatment of Vitillgo Patients
NCT05467839 ·Status: COMPLETED ·Phase: NA
-
Effects of Camouflage on the Life Quality of Patients With Vitiligo
NCT03540966 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo
NCT04774809 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Effectiveness of Narrow-band Ultraviolet B Combined With Topical Tacrolimus 0.03% in Treatment of Patients With Vitiligo
NCT03199664 ·Status: UNKNOWN ·Phase: PHASE4
-
T Central Memory Cells in Early Localized Non-Segmental Vitiligo
NCT05706636 ·Status: COMPLETED ·Phase: NA
-
Effectivness of Topical Tacrolimus Monotherapy in Patients With Vitiligo
NCT03358082 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.
NCT07174024 ·Status: COMPLETED ·Phase: PHASE4