Effect of Early Systemic Stabilization Therapy on Recent Onset Vitiligo
NCT05037981 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25
Last updated 2021-09-08
Summary
Vitiligo is a distressing disorder of depigmentation. In spite of multiple successful therapeutic regimens, disease relapse remains a challenge to patients and physicians. Most guidelines consider systemic treatments only in rapidly progressive disease with wider surface areas. This delay in halting the immune attack, may give the chance for further disease progression as well as establishment of resident memory T cell population predisposing to future disease relapses. The aim of this study was to assess the ability of early systemic therapy of localized (\<2% BSA), recent onset (\<6 months) vitiligo to control disease activity and minimize the possibility of recurrence.
Conditions
- Vitiligo
Sponsors & Collaborators
-
Cairo University
lead OTHER
Principal Investigators
-
Samia Esmat, MD · Cairo University
-
Rania Mogawer, MD · Cairo University
-
Dalia Bassiony, MD · Cairo University
-
Suzan Shalaby, MD · Cairo University
-
Rehab Hegazy, MD · Cairo University
-
Nanis Ragab, MD · Cairo University
-
Sarah Ibrahim · Cairo University
Eligibility
- Min Age
- 6 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-10-10
- Primary Completion
- 2021-08-10
- Completion
- 2021-08-20
More Related Trials
-
Improved Phototherapy in Patients With Vitiligo
NCT05836441 ·Status: UNKNOWN ·Phase: NA
-
T Central Memory Cells in Early Localized Non-Segmental Vitiligo
NCT05706636 ·Status: COMPLETED ·Phase: NA
-
Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis)
NCT01082393 ·Status: COMPLETED ·Phase: PHASE4
-
A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental Vitiligo
NCT07251595 ·Status: RECRUITING ·Phase: PHASE2
-
Safety and Efficacy of ARQ-252 Cream 0.3% in Subjects With Non-Segmental Facial Vitiligo
NCT04811131 ·Status: TERMINATED ·Phase: PHASE2
-
Topical Bimatoprost Solution 0.03%in Stable Vitiligo
NCT01202513 ·Status: WITHDRAWN ·Phase: PHASE4
-
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream With Phototherapy in Participants With Vitiligo
NCT05247489 ·Status: COMPLETED ·Phase: PHASE2
-
Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy
NCT03270241 ·Status: COMPLETED ·Phase: NA
-
Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo
NCT04774809 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
A Trial of SHR0302Base in Patients With Vitiligo
NCT06790862 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo
NCT04765826 ·Status: UNKNOWN ·Phase: NA
-
Effect of NB-UVB on the Tissue Level of IL 15 and IL-15Rα in Active Non Segmental Vitiligo Cases.
NCT05316987 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Autologous Outer-Root-Sheath Melanocytes Transplantation in the Treatment of Vitiligo
NCT01923142 ·Status: TERMINATED ·Phase: PHASE2
-
Latanoprost Plus NB-UVB Versus Each Alone in Non-segmental Vitiligo: Clinical and Laboratory Evaluation
NCT04811326 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparative Study Between Topical 5-fluorouracil and Latanoprost in Vitiligo.
NCT05513924 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
UVA1 Phototherapy in Acral Vitiligo
NCT03378011 ·Status: COMPLETED ·Phase: NA
-
Combined Therapy With Narrow-Band Ultraviolet B Phototherapy and Apremilast for the Treatment of Vitiligo
NCT03123016 ·Status: COMPLETED ·Phase: PHASE2
-
Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo
NCT00367224 ·Status: COMPLETED ·Phase: NA
-
Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation
NCT04245319 ·Status: UNKNOWN ·Phase: NA
-
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.
NCT06493578 ·Status: TERMINATED ·Phase: PHASE2
-
Randomized, Split-body, Single-blinded Clinical Trial of NB-UVB Treatment for Vitiligo
NCT02506101 ·Status: TERMINATED ·Phase: NA
-
Comparitive Study Between Uvb Alone and Uvb With Topical Tacrolimus 0.03% for the Treatment of Vitiligo
NCT05577637 ·Status: COMPLETED ·Phase: PHASE1
-
Promoting Repigmentation After Epidermal Cell Suspension Grafting and preVENTing the Loss of Melanocytes Using Topical Ruxolitinib for Vitiligo in Resistant Areas
NCT05872477 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Acral Vitiligo : Narrowband Ultraviolet-B and Microneedling With and Without Platelet Rich Plasma
NCT03155698 ·Status: UNKNOWN ·Phase: NA
-
The Evaluation of Vitiligous Lesions Repigmentation After Topical Administration of Methotrexate in Patients With Active Vitiligo
NCT04942860 ·Status: COMPLETED ·Phase: PHASE3