A Family-centred Approach Enhancing Cardiovascular Health in Ugandan Adolescents and Their Families

Summary

The FaCe-D Study, with funding from the Canadian Institute for Health Research (CIHR) through Global Alliance for Chronic Diseases (GACD) aims to adapt and implement an evidence-based family centred approach (FCA) to prevent cardiovascular diseases (CVD) among adolescents and their families. This 5-year implementation science study will be conducted in 16 villages in Jinja district and another 16 in Kampala beginning April 2024 to evaluate the effectiveness of FCA in reducing the risk of CVD in Uganda and to assess feasibility, adoption, while measuring the costs of implementation. The study will be implemented by a group of researchers from MRC/UVRI \& LSHTM, University of British Columbia (Canada), TASO (Uganda) and University of California San Francisco (UCSF) - USA with guidance from the Ministry of Health - Uganda.

Conditions

• Adolescent Behavior
• Lifestyle Modification
• Cardiovascular Disease Other

Interventions

BEHAVIORAL

The immediate (treatment) arm, will receive the FaCe-D intervention comprising of 'HOME VISITS, DIET, PHYSICAL ACTIVITY AND HEALTH MESSAGING

The participants will receive the FaCe-D intervention comprising of dietary and exercise interventions delivered by Village Health Teams (VHTs)

OTHER

Control Arm - standard of care

Arm Description: They will continue to receive standard care with VHts performing their usual roles of health promotion for both communicable and non-communicable diseases as outlined by the Ministry of Health guidelines. This standard care involves visits by the VHT at least once a quarter to check hygiene and environment, children's immunisation status and other health promotion activities. The VHT may or may not involve the entire family/household.

Sponsors & Collaborators

• University of California

  collaborator OTHER

• The AIDS Support Organization

  collaborator OTHER

• University of British Columbia

  collaborator OTHER

• MRC/UVRI and LSHTM Uganda Research Unit

  lead OTHER

Principal Investigators

• Prof Rachel King, PhD · University of California, San Francisco

• Prof David Moore, PhD · University of British Columbia

• Dr Josephine Birungi · MRC/UVRI and LSHTM Uganda Research Unit

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

10 Years

Max Age

19 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-07-05

Primary Completion

2027-01-31

Completion

2028-01-31

Countries

• Uganda

Study Locations