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Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

NCT07260071 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-12-02

No results posted yet for this study

Summary

The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance imaging (MRI) for rapid diagnosis alongside genetic testing. The main question it aims to answer is:

What is the prevalence of hypertension in a population sample of adolescents with ADPKD?

Participants will have the following measurements performed:

* Height and weight.
* Blood pressure.
* Non-invasive measurement of arterial stiffness.
* Cardiac and renal MRI.
* Blood sample.
* Genetic testing.

Conditions

  • Autosomal Dominant Polycystic Kidney Disease (ADPKD

Sponsors & Collaborators

Principal Investigators

  • Manish Sinha, PhD, MRCP (UK), MRCPCH · King's College London

Eligibility

Min Age
12 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-15
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07260071 on ClinicalTrials.gov