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The Effects of Chiropractic on Adults With Depression

NCT07260045 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-05-07

No results posted yet for this study

Summary

The goal of this clinical trial is to evaluate the feasibility of the study design in preparation for a future clinical trial examining chiropractic care for adults with mild to moderate depression. We aim to determine whether the study procedures function as intended, including the ability to recruit, retain, and engage participants, as well as whether the intervention is implemented as planned.

The main questions it aims to answer is:

1. Can sufficient eligible participants be enrolled within the planned timeframe?
2. Is there any retention of participant throughout the study duration and the factors contributing to ongoing participation?
3. Can participants adhere to pre-treatment instructions and protocols before their first check-up?
4. Can participants attend and complete all assessments and chiropractic sessions?
5. Can participants fulfill all required study activities without excessive burden?
6. Can chiropractors strictly follow chiropractic adjustments only, without offering any additional treatments?

Researchers will compare adults with depression on the waitlist group to see if chiropractic care effects on adults with depression.

Participants will

* Perform resting state Electrocardiography (ECG)
* Perform resting state Electroencephalography (EEG)
* Perform Event-related potential (ERP) à Auditory and visual stimuli tests
* Complete Patient Reported Outcomes (PROs)
* COMPASS-31
* PROMIS-29
* PROMIS-Cog-8
* Perceived Stress Scale
* Depression Short Form 8a
* Complete Assessment of Acceptability
* Complete Columbia Suicide Severity Rating Scale (C-SSRS)
* Receive 6 weeks of chiropractic care treatment

Conditions

  • Depression Disorder

Interventions

OTHER

Chiropractic Care

Participants of the treatment group will be randomly assigned to chiropractic care for 6 weeks. Participants will have their upper cervical spine (C1/C2) assessed for the presence of vertebral subluxations per the chiropractor's normal and customary procedures.

Sponsors & Collaborators

  • Life University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2027-03-01
Primary Completion
2028-03-01
Completion
2028-03-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07260045 on ClinicalTrials.gov