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Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy

NCT06388486 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 63

Last updated 2024-04-30

No results posted yet for this study

Summary

The goal of this observational study is to measure the levels of cytokine-induced transcription factor activation in a cohort of depressed inpatients undergoing psychotherapy. The study aims to answer the following main questions:

* Do psychological traits (i.e.: social inhibition, negative affectivity, ...) affect the activation of immunomodulatory transcription factors (STAT3, NFkB) in depressed patients?
* Are subjects with these psychological traits affected differently by psychotherapeutic intervention?

Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment. Peripheral blood mononuclear cells are isolated from the study subjects, and activation of transcription factors is measured by flow cytometry.

Conditions

Interventions

BEHAVIORAL

Psychotherapy

Subject receive psychotherapy during hospital treatment.

Sponsors & Collaborators

  • University Medical Center Goettingen

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2022-03-09
Completion
2024-01-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06388486 on ClinicalTrials.gov