IL-5 CAR-T Cell Therapy for Refractory/Relapsed Eosinophilic Leukemia
NCT07257640 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-12-10
Summary
This is an open-label, single-arm clinical study designed to evaluate the efficacy and safety of IL-5 CAR-T cell therapy in the treatment of patients with CD125-positive eosinophilic leukemia.
Conditions
- Hematologic Diseases
- Neoplasms
Interventions
- DRUG
-
IL-5 CAR-T cells
Each subject receive IL-5 CAR T-cells by intravenous infusion
Sponsors & Collaborators
-
Zhejiang University
lead OTHER
Principal Investigators
-
He Huang, MD · First Affiliated Hospital of Zhejiang University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-30
- Primary Completion
- 2028-11-30
- Completion
- 2028-11-30
Countries
- China
Study Locations
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