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Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia

NCT07252518 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2025-11-26

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10. The main questions it aims to answer are:

Does drug Pentoxifylline plus Coenzyme Q10 increase the motility of sperm in participants? What medical problems do participants have when taking drug Pentoxifylline plus Coenzyme Q10 ? Researchers will compare drug Pentoxifylline plus Coenzyme Q10 combination to Coenzyme Q10 alone to see if drug Pentoxifylline plus Coenzyme Q10 combination works better.

Participants will:

Experimental Group:Pentoxifylline 400mg twice dailyand Coenzyme Q10 100mg twice daily for 3 months.

Comparator Group: Coenzyme Q10 100mg twice daily for 3 months Visit the clinic after three months of treatment for checkups and tests

Conditions

  • Asthenozoospermia

Interventions

DIETARY_SUPPLEMENT

Coenzyme Q 10

Participants will receive Coenzyme Q10 100 mg twice daily for 3 months

COMBINATION_PRODUCT

Pentoxifylline 400 MG Oral Tablet

Participants will receive pentoxifylline 400mg twice daily plus coenzyme Q10 100mg twice daily for 3 months

Sponsors & Collaborators

  • Bangladesh Medical University

    collaborator OTHER

  • Mst.Sumyara Khatun

    lead OTHER

Principal Investigators

  • Jesmine Banu, MS · Bangladesh Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2026-07-01
Completion
2027-03-01

Countries

  • Bangladesh

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07252518 on ClinicalTrials.gov