SNAP AF-52: Dose Appropriateness and Adherence to Oral Anticoagulation in Adults ≥65 With Atrial Fibrillation in Primary Care (Ordu, Türkiye)
NCT07242326 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-02-25
Summary
SNAP AF-52 is an ambidirectional observational registry conducted in family health centers (primary care) across Ordu, Türkiye, enrolling adults ≥65 years with a pre-existing diagnosis of atrial fibrillation. The study assesses (a) label-concordant dosing of oral anticoagulants (DOACs/warfarin) using drug-specific criteria, and (b) medication adherence via Proportion of Days Covered (PDC) over the prior 12 months (good adherence defined as PDC ≥80%). Unsafe findings (e.g., suspected under-/overdosing, critical drug-drug interactions, very low renal function) trigger same-day referral to tertiary cardiology for evaluation and management. The retrospective window is Dec 1, 2024-Nov 30, 2025; the prospective single-visit inclusion window is Dec 1, 2025-May 31, 2026. No experimental treatment is administered; all care is routine.
Conditions
- Medication Adherence
- Atrial Fibrillation (AF)
- Direct Oral Anticoagulants (DOACs)
Sponsors & Collaborators
-
Ordu University Faculty of Medicine, Department of Cardiology
collaborator UNKNOWN -
Kotyora Family Medicine Health Management and Education Association
lead NETWORK
Principal Investigators
-
Seçkin Dereli, MD, Assoc. Prof. · Ordu University Faculty of Medicine, Department of Cardiology (Turkey)
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-15
- Primary Completion
- 2026-12-30
- Completion
- 2026-12-31
Countries
- Turkey (Türkiye)
Study Locations
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