Assessment of The Effect of Apixaban in AF

NCT03199521 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2019-02-07

No results posted yet for this study

Summary

This study will assess the effect of apixaban on thrombotic status in patients with atrial fibrillation.In addition it will compare apixaban to aspirin and warfarin on their effect on endogenous fibrinolysis.

Conditions

Interventions

OTHER

Thrombin generation assays, Thromboelastography (TEG), and Global Thrombosis Test (GTT)

Global Thrombosis Test (GTT): assesses formation of the blood clot and how easily can this be broken down once formed) Thromboelastography (TEG) :assesses the properties of a blood clot and how easily can be broken down Thrombin generation assays: assesses the formation of a blood clot and the potential of thrombolysis via the introduction of different buffer solutions

Sponsors & Collaborators

  • University of Hertfordshire

    collaborator OTHER
  • East and North Hertfordshire NHS Trust

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2019-01-02
Completion
2019-01-02

Countries

  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03199521 on ClinicalTrials.gov