Assessment of The Effect of Apixaban in AF
NCT03199521 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 240
Last updated 2019-02-07
Summary
This study will assess the effect of apixaban on thrombotic status in patients with atrial fibrillation.In addition it will compare apixaban to aspirin and warfarin on their effect on endogenous fibrinolysis.
Conditions
- Atrial Fibrillation
- Embolism Thrombosis
Interventions
- OTHER
-
Thrombin generation assays, Thromboelastography (TEG), and Global Thrombosis Test (GTT)
Global Thrombosis Test (GTT): assesses formation of the blood clot and how easily can this be broken down once formed) Thromboelastography (TEG) :assesses the properties of a blood clot and how easily can be broken down Thrombin generation assays: assesses the formation of a blood clot and the potential of thrombolysis via the introduction of different buffer solutions
Sponsors & Collaborators
-
University of Hertfordshire
collaborator OTHER -
East and North Hertfordshire NHS Trust
lead OTHER_GOV
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-06-01
- Primary Completion
- 2019-01-02
- Completion
- 2019-01-02
Countries
- United Kingdom
Study Locations
More Related Trials
-
Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation
NCT05321810 ·Status: COMPLETED
-
Trial of Apixaban vs Warfarin in Reducing Rate of Cognitive Decline, Silent Cerebral Infarcts and Cerebral Microbleeds in Patients With Atrial Fibrillation
NCT03839355 ·Status: TERMINATED ·Phase: PHASE3
-
APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF
NCT02789917 ·Status: COMPLETED ·Phase: PHASE4
-
Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs DOACs)
NCT03568916 ·Status: COMPLETED
-
Apixaban in Patients With Left Ventricular Thrombus
NCT05208398 ·Status: COMPLETED ·Phase: PHASE3
-
Atrial Fibrillation Feasibility Certoparin Trial - AFFECT
NCT00171769 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Apixaban in Korean Frail Atrial Fibrillation Patient
NCT05773222 ·Status: ACTIVE_NOT_RECRUITING
-
A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart
NCT02415400 ·Status: COMPLETED ·Phase: PHASE4
-
Therapy With New Oral Anticoagulants
NCT02222090 ·Status: UNKNOWN
-
Safety and Effectiveness of Apixaban in Very Elderly Patients With Non-valvular Atrial Fibrillation (NVAF) Compared to Warfarin Using Administrative Claims Data
NCT05438888 ·Status: COMPLETED
-
Safety and Efficacy of Apixaban in Very Old Geriatric Subjects (> 80 Years) With Atrial FIbrillation in a Prospective reAl World Study;
NCT04586972 ·Status: COMPLETED
-
Effect of Antithrombotic Treatment in Patients With Both Coronary Heart Disease and Atrial Fibrillation
NCT03051061 ·Status: UNKNOWN
-
Hirudin Plus Aspirin in the Secondary Prevention of Cardioembolic Stroke Due to Nonvalvular Atrial Fibrillation
NCT02181361 ·Status: COMPLETED
-
Replication of the ARISTOTLE Anticoagulant Trial in Healthcare Claims Data
NCT04593030 ·Status: COMPLETED
-
Prevention of Venous Obstruction After Implantation of Cardiac Pacemaker and Defibrillator
NCT02331511 ·Status: UNKNOWN ·Phase: NA
-
Safety Study of Apixaban in Recent Acute Coronary Syndrome
NCT00313300 ·Status: COMPLETED ·Phase: PHASE2
-
Apixaban After Anticoagulation-associated Intracerebral Haemorrhage in Patients With Atrial Fibrillation
NCT02565693 ·Status: COMPLETED ·Phase: PHASE2
-
Antithrombotic Triple Therapy in Humans
NCT01812200 ·Status: COMPLETED ·Phase: PHASE4
-
Prospective Real-world Registry Describing Treatment Regimens
NCT03942913 ·Status: UNKNOWN
-
Clinical Trial to Improve Treatment With Blood Thinners in Patients With Atrial Fibrillation
NCT02082548 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of MAA868 in Patients With Atrial Fibrillation
NCT03398434 ·Status: WITHDRAWN ·Phase: PHASE2
-
Real-World Evidence of Anticoagulation Treatment In Non-Valvular Atrial Fibrillation In Italy
NCT02921126 ·Status: COMPLETED
-
Apixaban Dose Reduction in Patients With Elevated Drug Levels
NCT02809469 ·Status: UNKNOWN ·Phase: PHASE2
-
Impact of Dabigatran and Phenprocoumon on ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation
NCT01339819 ·Status: COMPLETED ·Phase: PHASE4
-
Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement
NCT00465218 ·Status: COMPLETED