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Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee Arthroplasty

NCT07239999 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 170

Last updated 2026-02-06

No results posted yet for this study

Summary

This study or clinical trial looking to compare 2 types of freezing medications injected into the spinal fluid at the lower back between the vertebrae in patients going to have total knee replacement surgery to check for early legs movement, early discharge from recovery room, walking and hospital discharge. This could save hospital cost of such procedures.

Conditions

  • Recovery Period
  • Anesthesia

Interventions

DRUG

Mepivacaine Injection

Comparing time to motor block recovery in PACU, time to PACU discharge, time to ambulation and length of hospital stay

DRUG

Chloroprocaine Injection

Comparing time to motor block recovery in PACU, time to PACU discharge, time to ambulation and length of hospital stay

Sponsors & Collaborators

  • Nova Scotia Health Authority

    lead OTHER

Principal Investigators

  • HUSAM M NASHNOUSH, MBBCH, FRCPC · Dalhousie University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-31
Primary Completion
2027-04-04
Completion
2027-06-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07239999 on ClinicalTrials.gov