MedTrace Logo

Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration

NCT01012232 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2009-11-11

No results posted yet for this study

Summary

In a randomized, double-blind, cross-over trial, 48 patients scheduled for total knee arthroplasty with placement of an intracapsular catheter will be randomized to receive bolus injection of ropivacaine in high volume/low concentration (20 ml, 5 mg/mL) or low volume/high concentration (10 mL, 10 mg/mL) 6 and 24 hours postoperatively, and pain will be assessed at rest and with mobilization for 2 hours after injections.

Conditions

  • Postoperative Pain
  • Analgesic Efficacy

Interventions

DRUG

20 mL ropivacaine 5 mg/mL

DRUG

10 mL ropivacaine 10 mg/mL

Sponsors & Collaborators

  • Lundbeck Foundation

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-06-30
Primary Completion
2009-10-31
Completion
2009-10-31

Countries

  • Denmark

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01012232 on ClinicalTrials.gov