Understanding Cauda Equina Syndrome

NCT07235579 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 621

Last updated 2025-11-19

No results posted yet for this study

Summary

Cauda equina syndrome is a potentially devastating condition caused by compression of the cauda equina nerve roots. This can result in bowel, bladder and sexual dysfunction plus lower limb weakness, numbness, and pain. Cauda equina syndrome occurs infrequently but has serious potential morbidity and medico-legal consequences. This study aims to identify and describe the presentation and management of patients with cauda equina syndrome in the United Kingdom using trainee research collaborative networks. This will provide accurate incidence figures, establish current clinical practice, allow assessment of the adherence to national published standards of care, and determine patient outcomes from this condition. Accurate, up to date information about the presentation, management, and outcome of patients with cauda equina syndrome will inform standards of service design and delivery for this important but infrequent condition and help to identify future research priorities.

Conditions

  • Cauda Equina Syndrome

Sponsors & Collaborators

  • NHS Lothian

    collaborator OTHER_GOV
  • University Hospitals of Derby and Burton NHS Foundation Trust

    collaborator OTHER
  • Royal Brompton & Harefield NHS Foundation Trust

    collaborator OTHER
  • East Kent Hospitals University NHS Foundation Trust

    collaborator OTHER_GOV
  • Somerset NHS Foundation Trust

    collaborator OTHER
  • Buckinghamshire Healthcare NHS Trust

    collaborator OTHER
  • Milton Keynes University Hospital NHS Foundation Trust

    collaborator OTHER_GOV
  • The Ipswich Hospital NHS Trust

    collaborator OTHER
  • King's College Hospital NHS Trust

    collaborator OTHER
  • Newcastle-upon-Tyne Hospitals NHS Trust

    collaborator OTHER
  • University Hospital Southampton NHS Foundation Trust

    collaborator OTHER
  • Royal Devon and Exeter NHS Foundation Trust

    collaborator OTHER
  • Royal Cornwall Hospitals Trust

    collaborator OTHER
  • Walton Centre NHS Foundation Trust

    collaborator OTHER
  • South Tees Hospitals NHS Foundation Trust

    collaborator OTHER
  • Lancashire Teaching Hospitals NHS Foundation Trust

    collaborator OTHER
  • City Hospitals Sunderland NHS Foundation Trust

    collaborator OTHER
  • Northern Care Alliance NHS Foundation Trust

    collaborator OTHER
  • Hull University Teaching Hospitals NHS Trust

    collaborator OTHER_GOV
  • The Leeds Teaching Hospitals NHS Trust

    collaborator OTHER
  • Sheffield Teaching Hospitals NHS Foundation Trust

    collaborator OTHER
  • Nottingham University Hospitals NHS Trust

    collaborator OTHER
  • University Hospital Birmingham NHS Foundation Trust

    collaborator OTHER
  • University Hospitals Coventry and Warwickshire NHS Trust

    collaborator OTHER
  • Cambridge University Hospitals NHS Foundation Trust

    collaborator OTHER
  • Norfolk and Norwich University Hospitals NHS Foundation Trust

    collaborator OTHER
  • Oxford University Hospitals NHS Trust

    collaborator OTHER
  • North Bristol NHS Trust

    collaborator OTHER
  • University Hospital Plymouth NHS Trust

    collaborator OTHER
  • Barts & The London NHS Trust

    collaborator OTHER
  • Barking, Havering and Redbridge University Hospitals NHS Trust

    collaborator OTHER
  • Brighton and Sussex University Hospitals NHS Trust

    collaborator OTHER
  • St George's University Hospitals NHS Foundation Trust

    collaborator OTHER
  • University College London Hospitals

    collaborator OTHER
  • Imperial College Healthcare NHS Trust

    collaborator OTHER
  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Julie Woodfield, MBChB PhD · University of Edinburgh

  • Aimun Jamjoom · University of Edinburgh

  • Ingrid Hoeritzauer, MBBChBAO · University of Edinburgh

Eligibility

Min Age
18 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2022-01-08
Completion
2022-01-08

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07235579 on ClinicalTrials.gov