A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight
NCT07232719 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2026-04-17
Summary
The purpose of this study is to evaluate the efficacy and safety of retatrutide compared with placebo for body weight reduction.
Participation in the study will last about 65 weeks and may include about 18 visits.
Conditions
Interventions
- DRUG
-
Administered SC
- DRUG
-
Administered SC
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-17
- Primary Completion
- 2027-07-31
- Completion
- 2027-07-31
- FDA Drug
- Yes
Countries
- United States
- United Kingdom
Study Locations
More Related Trials
-
A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee
NCT05931367 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
NCT04881760 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
NCT05936151 ·Status: COMPLETED ·Phase: PHASE2
-
Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.
NCT03856047 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
NCT07215559 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
NCT06047548 ·Status: COMPLETED ·Phase: PHASE3
-
Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin
NCT02963922 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
NCT07321886 ·Status: RECRUITING ·Phase: PHASE3
-
Methodology Study To Examine 6-Week Food Intake With Liraglutide In Obese Subjects
NCT03041792 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
NCT05929066 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities
NCT05051579 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity
NCT03523273 ·Status: COMPLETED ·Phase: PHASE2
-
Research Study Investigating Study Medicine (NNC9204-1177) for Weight Management in People With Overweight or Obesity
NCT03308721 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes
NCT06603571 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
NCT06037252 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight
NCT06683508 ·Status: COMPLETED ·Phase: PHASE2
-
Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity
NCT04074161 ·Status: COMPLETED ·Phase: PHASE3
-
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
NCT06143956 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
NCT06124807 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY3841136 in Healthy and Overweight Participants
NCT05295940 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943
NCT06313528 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
NCT04657016 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or Obesity
NCT03479892 ·Status: COMPLETED ·Phase: PHASE1
-
Lifestyle Modification and Liraglutide
NCT02911818 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of LY3841136 in Overweight and Obese Participants
NCT06345066 ·Status: COMPLETED ·Phase: PHASE1