Time Window for Ischemic Stroke First Mobilization Effectiveness

Summary

Early mobilization was thought to be effective in patients with acute ischemic stroke. As the essential component of stroke unit care, early mobilization has already been part of routine clinical practice. However, it is uncertain that which and when medical service focusing on functional recovery should be delivered after the emergency interventions for stroke. Besides, the optimal time window, for delivering early mobilization after acute ischemic stroke, has not been verified with strong evidence.

Conditions

• Brain Ischemia
• Stroke Rehabilitation

Interventions

OTHER

early rehabilitation

The three study groups share a same intervention protocol in addition to the initiation timing of intervention from the stroke onset. The frequency and intensity of the intervention is titrated according to functional activity baseline and monitored daily and adjusted with recovery. Encourage patients to move out of bed as soon as possible. Definition of bed movement: Encourage and help patients to perform functional actions, focusing on activities such as sitting, standing, walking out of the bed.

Sponsors & Collaborators

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• The Affiliated Hospital of Xuzhou Medical University

  collaborator OTHER

• Nanjing Tongren Hospital

  collaborator OTHER

• The First Affiliated Hospital of Soochow University

  collaborator OTHER

• Nanjing Jiangbei People's Hospital

  collaborator OTHER

• The First People's Hospital of Lianyungang

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• Zibo Central Hospital

  collaborator OTHER_GOV

• Liaocheng People's Hospital

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Xingtai People's Hospital

  collaborator OTHER

• The First Hospital of Hebei Medical University

  collaborator OTHER

• Cangzhou Central Hospital

  collaborator OTHER

• Anhui Provincial Hospital

  collaborator OTHER_GOV

• The First Affiliated Hospital of Bengbu Medical University

  collaborator OTHER

• Jingmen No.1 People's Hospital

  collaborator OTHER

• Wuhan University

  collaborator OTHER

• Hainan General Hospital

  collaborator OTHER

• The First Affiliated Hospital of Shanxi Medical University

  collaborator OTHER

• Shanghai Pudong Hospital

  collaborator OTHER

• Tianjin Medical University General Hospital

  collaborator OTHER

• Chongqing Three Gorges Central Hospital

  collaborator OTHER

• First Affiliated Hospital of Fujian Medical University

  collaborator OTHER

• First People's Hospital of Yulin

  collaborator OTHER

• First Affiliated Hospital of Xinjiang Medical University

  collaborator OTHER

• China Stroke Databank Center

  lead OTHER

Principal Investigators

• Lu Xiao, MD/PHD · The First Affiliated Hospital with Nanjing Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-08-13

Primary Completion

2022-10-31

Completion

2022-12-31

Countries

• China

Study Locations