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Intrathecal Morphine for Recovery and Outcomes After VATS

NCT07231926 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-02-05

No results posted yet for this study

Summary

This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS). One group will receive a combination of spinal morphine, nerve block, and dexmedetomidine, while the other group will receive a nerve block and dexmedetomidine without spinal morphine. All patients will receive standard pain medications after surgery. The purpose is to see if adding spinal morphine improves pain control and recovery after surgery.

Conditions

  • Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery

Interventions

PROCEDURE

Serratus Anterior Plane Block (SAPB) group

Ultrasound-guided unilateral SAPB at end of surgery with 30 mL 0.25% bupivacaine.

DRUG

Dexmedetomidine

Loading dose 0.5 µg/kg over 15 minutes, then 0.5 µg/kg/h continuous infusion intraoperatively.

DRUG

Intrathecal Morphine

200 µg morphine sulfate, single-dose via L3-L4, 27G Sprotte spinal needle, prior to induction.

Sponsors & Collaborators

  • Ataturk University

    lead OTHER

Principal Investigators

  • İREM ATEŞ · Ataturk University

  • Nuray Uzun · Ataturk University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2026-06-01
Completion
2026-06-02

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07231926 on ClinicalTrials.gov