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Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation

NCT07208643 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2026-04-28

No results posted yet for this study

Summary

This prospective study will include patients previously enrolled in the PER-ECL-2019-05 trial who attend the Department of Periodontology (CUO) for maintenance therapy or treatment of periodontal and/or peri-implant diseases, provided they meet the inclusion criteria.

Initially, 36 patients with advanced peri-implantitis were enrolled in a randomized clinical trial evaluating the clinical, radiographic and patient-related outcomes of reconstructive therapy following a non-surgical phase of peri-implantitis treatment compared to non-surgical treatment alone (PER-ECL-2019-05) (10).

At the study conclusion 34 patients were re-evaluated and 2 patients were excluded from the study (10).

In the original study, adult patients presenting at least one titanium implant diagnosed with peri-implantitis were identified among patients referred to the Department of Periodontology of UIC between January 2020 and October 2022. Peri-implantitis was diagnosed following the case definition of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions (11) that is, PPD ≥ 6 mm combined with bleeding on probing (BOP) and/or suppuration (SUP), together with progressive bone loss in relation to the radiographic bone level assessment. In those cases where initial radiograph was unavailable, the definition of a peri-implantitis case was based on radiographic evidence of bone level ≥3 mm apical to the most coronal portion of the intra-osseous part of the implant (12).

At the outset of the original study, participants were randomly assigned to one of two groups:

The first group received only non-surgical therapy for peri-implantitis, while the second group underwent a non-surgical phase followed by reconstructive surgical treatment. This design allowed for direct comparison of the clinical, radiographic, and patient-centered outcomes between the two treatment modalities. Both groups were managed and evaluated according to standardized protocols, ensuring consistency and reliability of the results at 12 months .

Patients who have not returned to the Department will be contacted by telephone and invited to participate through the academic office.

At 36 months, a single follow-up will be carried out including:

A detailed clinical examination. A standardized radiographic assessment.

Conditions

  • Peri-implantitis

Sponsors & Collaborators

  • Ramón Pons Calabuig

    lead OTHER

Principal Investigators

  • CRISTINA VALLES CS VALLES, PhD · Universitat Internacional de Catalunya

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-01
Primary Completion
2026-05-01
Completion
2026-05-01

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07208643 on ClinicalTrials.gov