Identifying Genetic Targets in Gynecological Tumors
NCT07169396 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180
Last updated 2025-09-11
Summary
This observational study aims to identfy genetic targets involved in the pathogenesis of gynecological tumors, with a focus on high-grade serous ovarian carcinoma. Using a triple approach - in silico, ex vivo and in vitro - the study will investigate the role of gonadotropins and their related signaling pathways in the epithelial ovarian cancers. Gene and protein expression levels will be evaluated through transcriptomic analysis, immunohistochemistry and functional assays on tumor cell lines. The goal is to uncover potential diagnostic or therapeutic targets in gynecological malignancies.
Conditions
Interventions
- OTHER
-
RNA extraction and gene expression
RNA extraction and gene expression
Sponsors & Collaborators
-
Azienda USL Reggio Emilia - IRCCS
lead OTHER_GOV
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-11-17
- Primary Completion
- 2021-11-17
- Completion
- 2027-11-30
Countries
- Italy
Study Locations
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