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Systems Oncology Approach to Optimize Ovarian Cancer Treatment

NCT06117384 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-11-07

No results posted yet for this study

Summary

The overall aim is to identify effective therapeutic strategies to ovarian cancer (OC) using serial tumor, ascites and blood samples, and carry out state-of-the-art sequencing approaches, functional assays and associated bioinformatics to understand mechanisms behind chemoresistance in OC and identify new treatment options for OC patients. In this observational trial, we will systematically collect, analyze and interpret functional, molecular and clinical data from real-world ovarian cancer patients.

Conditions

Interventions

GENETIC

Biomolecular profiling

Molecular and functional analysis of biospecimens, including tumor-normal Whole-exome sequencing, bulk and single-cell RNAsequencing, spatial proteomics, functional testing.

Sponsors & Collaborators

  • Helsinki University Central Hospital

    collaborator OTHER

  • University of Helsinki

    lead OTHER

Principal Investigators

  • Anniina Färkkilä, MD PhD · Helsinki University Central Hospital

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-01
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Finland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06117384 on ClinicalTrials.gov