Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain

NCT07163065 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2025-09-09

No results posted yet for this study

Summary

This study aims to investigate the relationship between systemic inflammatory markers and the effectiveness of inferior alveolar nerve block anesthesia in patients undergoing dental treatment. The primary focus is on the Systemic Inflammatory Index (SII) and other inflammatory biomarkers, and how they may influence both the success of anesthesia and the intensity of postoperative pain. By analyzing blood samples and clinical outcomes, the study will provide new insights into the role of systemic inflammation in anesthesia effectiveness and postoperative pain control. The findings may help clinicians predict anesthetic success and improve pain management strategies in dental practice.

Conditions

  • Postoperative Pain
  • Inferior Alveolar Nerve Block Failure
  • Inflammation Biomarkers
  • Dental Anesthesia Complications

Interventions

PROCEDURE

Inferior Alveolar Nerve Block Anesthesia

Standard inferior alveolar nerve block anesthesia performed with lidocaine and epinephrine for mandibular dental treatment. Success rate and postoperative pain outcomes will be recorded

Sponsors & Collaborators

  • KEZBAN MELTEM ÇOLAK

    lead OTHER

Principal Investigators

  • KEZBAN MELTEM ÇOLAK · Atatürk University, Faculty of Dentistry, Department of Endodontics

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-27
Primary Completion
2024-11-01
Completion
2025-10-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07163065 on ClinicalTrials.gov