Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain
NCT07163065 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-09-09
Summary
This study aims to investigate the relationship between systemic inflammatory markers and the effectiveness of inferior alveolar nerve block anesthesia in patients undergoing dental treatment. The primary focus is on the Systemic Inflammatory Index (SII) and other inflammatory biomarkers, and how they may influence both the success of anesthesia and the intensity of postoperative pain. By analyzing blood samples and clinical outcomes, the study will provide new insights into the role of systemic inflammation in anesthesia effectiveness and postoperative pain control. The findings may help clinicians predict anesthetic success and improve pain management strategies in dental practice.
Conditions
- Postoperative Pain
- Inferior Alveolar Nerve Block Failure
- Inflammation Biomarkers
- Dental Anesthesia Complications
Interventions
- PROCEDURE
-
Inferior Alveolar Nerve Block Anesthesia
Standard inferior alveolar nerve block anesthesia performed with lidocaine and epinephrine for mandibular dental treatment. Success rate and postoperative pain outcomes will be recorded
Sponsors & Collaborators
-
KEZBAN MELTEM ÇOLAK
lead OTHER
Principal Investigators
-
KEZBAN MELTEM ÇOLAK · Atatürk University, Faculty of Dentistry, Department of Endodontics
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-27
- Primary Completion
- 2024-11-01
- Completion
- 2025-10-15
Countries
- Turkey (Türkiye)
Study Locations
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