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The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy

NCT07130214 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2025-11-18

No results posted yet for this study

Summary

This study employs saliva-based DNA analysis to investigate the effect of genetic polymorphisms, particularly SNPs in MMP, TIMP, TNF-α, and BMP genes, on the success of vital pulp therapy in permanent teeth with pulpitis, assessed through clinical follow-up.

Conditions

  • Pulp Exposure, Dental
  • Pulp Disease, Dental
  • Pulp Caping
  • Pulpitis
  • Pulpitis - Irreversible
  • Pulpal Inflammation

Interventions

DRUG

Biodentine

Biodentine is used in the treatment of existing dentin damage thanks to active bio-silicate technology.

Sponsors & Collaborators

  • Health Institutes of Turkey

    collaborator OTHER_GOV

  • Ataturk University

    lead OTHER

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-02
Primary Completion
2026-05-02
Completion
2026-11-02
FDA Drug
Yes

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07130214 on ClinicalTrials.gov