REACT - Resistance Exercise After Cancer Treatment

Summary

Resistance exercise has been shown to improve several important health variables after cancer and cancer related treatment, but unfortunately the adherence to resistance exercise is low. Typical reported exercise barriers are inconvenient location (e.g. long distance from home), exercise at an unfavorable time of the day, inadequate access to cancer-specific exercise and insufficient recommendations from healthcare providers. Thus, there is need for more research on resistance exercise with an alternative approach in cancer rehabilitation, that potentially can target a broad range of patients, despite their domicile. In Norway, the foundation "Active against cancer" has established exercise locations targeting cancer patients in several hospitals, and today they also offer digital home-based exercise sessions. Therefore, the overall research objectives are to compare the efficacy of a 12 weeks digital, home-based resistance exercise program for cancer patients after treatment on functional, mental, and metabolic health, compared to the same program conducted in a studio under guidance of an instructor. The primary aim is to compare the effect on exercise adherence between digital home-based exercise program and the on-site guided program in cancer patients after treatment. Secondary aims are to compare the two groups on several functional health outcomes, mental health outcomes and metabolic health markers. In addition to the randomized controlled trial, the project includes two non-randomized cohorts - patients undergoing active cancer treatment, and patients living more than 20 km from an exercise location - who follow the digital home-based program and the same test protocol.

Conditions

• Cancer

Interventions

OTHER

Digital follow-up

See the arm/group description.

OTHER

On-site follow-up

See the arm/group description.

BEHAVIORAL

Resistance exercise

See the arm/group description.

Sponsors & Collaborators

• Sykehuset Innlandet HF

  collaborator OTHER

• Inland Norway University of Applied Sciences

  lead OTHER

Principal Investigators

• Stian Ellefsen, Professor · Inland Norway University of Applied Sciences

• Arne Kolstad, Professor · Sykehuset Innlandet HF

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-08-01

Primary Completion

2026-06-15

Completion

2028-06-30

Countries

• Norway

Study Locations