Outcome of Use of a Novel Modulator of Oxidative Phosphorylation on Kidney Function in Patients With Progressive Chronic Kidney Disease

Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NCT04344769 ·Status: RECRUITING

A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease

NCT06734234 ·Status: RECRUITING ·Phase: PHASE1

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

NCT04580420 ·Status: RECRUITING ·Phase: PHASE2

A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001]

NCT00841568 ·Status: COMPLETED ·Phase: PHASE2

Pentoxifylline on Inflammatory Markers in Non-Diabetic Chronic Kidney Disease Patients

NCT07315139 ·Status: COMPLETED ·Phase: NA

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

NCT00805090 ·Status: COMPLETED ·Phase: PHASE1

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

NCT02837237 ·Status: COMPLETED ·Phase: PHASE1

A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Effects of Ferric Citrate in Subjects With End Stage Renal Disease

NCT01503736 ·Status: COMPLETED ·Phase: PHASE3

Pharmacokinetics and Pharmacodynamics of Apixaban in Subjects on Hemodialysis

NCT01340586 ·Status: COMPLETED ·Phase: PHASE1

Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis

NCT00704483 ·Status: COMPLETED ·Phase: PHASE2

A Study of Enlicitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Participants With Moderate Renal Impairment (MK-0616-007)

NCT05070390 ·Status: COMPLETED ·Phase: PHASE1

Role of ROS and cAMP-PKA Biomarkers in ADPKD

NCT07217158 ·Status: ACTIVE_NOT_RECRUITING

Multiple Doses of DM199 in Patients With Chronic Kidney Disease (REDUX)

NCT04123613 ·Status: COMPLETED ·Phase: PHASE2

Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia

NCT00772382 ·Status: COMPLETED ·Phase: PHASE3

Pentoxifylline and Progression of Chronic Kidney Disease in Moderate-to-high Risk Patients

NCT00285298 ·Status: COMPLETED ·Phase: PHASE3

Efficacy of Pentoxifylline on Chronic Kidney Disease

NCT00155246 ·Status: COMPLETED ·Phase: PHASE4

Optimal Titration Regimen for SBR759 in Lowering Serum Phosphate Levels in Asian Chronic Kidney Disease Patients on Hemodialysis

NCT00704678 ·Status: COMPLETED ·Phase: PHASE2

Efficacy of Pentoxifylline on Primary Nephrotic Syndrome

NCT00354731 ·Status: COMPLETED ·Phase: PHASE3

Dose-finding Study of KHK7791 in Hyperphosphatemia Patients

NCT03864458 ·Status: COMPLETED ·Phase: PHASE2

A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function

NCT07315360 ·Status: RECRUITING ·Phase: PHASE1

A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004)

NCT00683553 ·Status: TERMINATED ·Phase: PHASE1

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis

NCT05624723 ·Status: COMPLETED ·Phase: PHASE1

Exercise Intolerance in Renal Failure

NCT01356966 ·Status: COMPLETED ·Phase: PHASE2

A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis

NCT01191255 ·Status: COMPLETED ·Phase: PHASE3

Bosutinib In Subjects With Renal Impairment

NCT01233882 ·Status: COMPLETED ·Phase: PHASE1