MedTrace Logo

Virtual Reality Intervention for Symptom Management in Stem Cell Transplantation

NCT07145359 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-08-28

No results posted yet for this study

Summary

The goal of this clinical trial is to evaluate whether a virtual reality (VR) intervention based on the Symptom Management Model can reduce physical and psychosocial symptoms during hematopoietic stem cell transplantation (HSCT) in adult patients undergoing allogeneic transplantation.

The main questions it aims to answer are:

Does the VR intervention reduce distress levels during HSCT?

Does the VR intervention decrease state anxiety and symptom severity compared to standard care?

Does the VR intervention positively affect physiological outcomes and engraftment times?

Researchers will compare a group receiving standard clinical care plus a VR nature-themed video during HSCT to a group receiving standard care only to see if the VR intervention improves symptom management outcomes.

Participants will:

Be randomly assigned to either the intervention or control group.

In the intervention group:

Watch a 15-minute nature-themed VR video during stem cell infusion using Meta Quest 3.

The video content will be specifically created by the research team based on the principles of Attention Restoration Theory (ART).

In both groups:

Complete pre- and post-intervention assessments including:

Distress Thermometer

State-Trait Anxiety Inventory

Edmonton Symptom Assessment Scale

Physiological measures (vital signs)

Engraftment tracking

Satisfaction and open-ended feedback forms

Conditions

  • Cancer and / or Hematological Malignancy
  • Hematopoetic Stem Cell Transplantation
  • Nursing Interventions
  • Symptom Management
  • Virtual Reality
  • ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

Interventions

OTHER

Virtual Reality Intervention

This intervention is distinguished by its integration of a structured, nurse-led virtual reality (VR) protocol specifically designed for symptom management during hematopoietic stem cell transplantation (HSCT). Unlike general VR distraction methods used in oncology, this intervention employs video content created by the research team in accordance with Attention Restoration Theory (ART), offering five preselected nature-themed options tailored to patient preferences. Prior to the procedure, eligible patients are introduced to the intervention one day in advance and given the opportunity to trial the VR equipment, ask questions, and select their preferred video. During the infusion, VR is initiated exactly one minute before the stem cell procedure and ends at the 15th minute, as recommended by the literature. Symptom assessments are conducted immediately before and after the intervention using validated tools, including the Distress Thermometer, State Anxiety Inventory, and the Edmonto

Sponsors & Collaborators

  • Halic University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-10
Primary Completion
2026-06-10
Completion
2026-09-10

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07145359 on ClinicalTrials.gov