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The Effects of Prayer on Pain Thresholds and Scores of Anxiety and Depression in Patients With Migraine and Control

NCT07143461 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 105

Last updated 2026-02-25

No results posted yet for this study

Summary

The objective of this randomized single-blind crossover study is to evaluate the effect of prayer compared to the practice of reading a text (control) on the pressure pain threshold in individuals with and without migraine. The main topics it aims to answer are:

* To analyze the relationship between individuals' spirituality, pain thresholds, and anxiety and depression scores.
* To evaluate the effects of different aspects of prayer (thanksgiving, adoration, confession, meditative, and petitionary) on cephalic pain thresholds in individuals with and without migraines.

Migraine group: 50 participants. Non-migraine group: 50 participants. Total number of participants in total: 100.

Conditions

Interventions

BEHAVIORAL

Faith Healing

Participants will perform a 10-minute session of silent personal prayer using a prayer they are already familiar with and commonly practice. Participants will be instructed to pray in their usual way without vocalization, focusing on the content/meaning of the prayer. If distracted, they will be asked to gently refocus on prayer.

BEHAVIORAL

Control

In the control condition, participants will read a neutral text with no spiritual or religious content for 10 minutes. If distracted, they should refocus on the text.

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-09-29
Primary Completion
2025-09-29
Completion
2025-09-29

Countries

  • Brazil

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07143461 on ClinicalTrials.gov