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Effect of Manual Therapy on Migraine in Postmenopausal Women

NCT07127107 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-08-17

No results posted yet for this study

Summary

The purpose of the study is to determine the effect of manual therapy on migraine in postmenopausal women.

Conditions

Interventions

DRUG

Non-steroidal anti-inflammatory drugs (NSAIDs)

For mild and moderate migraines e.g Ibuprofen and aspirin. * Aspirin: Peroral (PO) tablet with standard dosages of 325 mg, 500 mg, and 400 mg effervescent; treatment dosage of up to 1000 mg * Ibuprofen: PO tablet with standard dosages of 200 mg, 400 mg, 600 mg, and 800 mg; treatment dosage of 200 to 800 mg

OTHER

Manual therapy techniques

Cranial manipulative osteopathy: Tension release of cranial sutures is applied while the patient in supine lying position, a pressure of 200g to3kg is applied with both thumbs for 30-40 sec or till release occurs. it includes: 1. Coronal suture The head is directed to one side and the pressure is applied with both thumbs directed parallel to each otheralong the coronal suture. 2. Sagital suture distraction The head is in the central position and the pressure is applied with both thumbs directed parallel to each other along the sagittal suture. 3. Squamous suture distraction The head is directed to one side and the pressure is applied with both thumbs parallel along the squamous suture. 4. Lamboidal suture distraction: The head is directed to one side and the thumbs directed parallel to each other along the lamboidal suture. 5. Occipitomastoid suture distraction The head is directed to one side and both thumbs directed parallel to each other along occipitomastoid suture.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Hala Mahmoud, Professor · Cairo University

  • Amel Youssef, Professor · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-20
Primary Completion
2026-02-20
Completion
2026-03-10

Countries

  • Egypt

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07127107 on ClinicalTrials.gov