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Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines

NCT07142369 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 99

Last updated 2026-02-12

No results posted yet for this study

Summary

The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (ACL) rupture of the knee.

Conditions

  • Posttraumatic Osteoarthritis
  • Anterior Cruciate Ligament (ACL) Rupture

Interventions

PROCEDURE

Synovial Fluid withdrawal at the preoperative clinic visit

Synovial Fluid withdrawal at the preoperative clinic visit

PROCEDURE

Platelet-Rich Plasma (PRP) preparation and injection

Platelet-Rich Plasma (PRP) preparation and injection

PROCEDURE

Synovial fluid withdrawal at the time of surgery

Synovial fluid withdrawal at the time of surgery

PROCEDURE

3mL synovial fluid withdrawn at the preoperative visit

3mL synovial fluid withdrawn at the preoperative visit

Sponsors & Collaborators

  • Arthroscopy Association of North America (AANA)

    collaborator UNKNOWN

  • Rush University Medical Center

    lead OTHER

Principal Investigators

  • Adam Yanke, MD, PhD · Associate Professor and Surgeon

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-31
Primary Completion
2028-10-31
Completion
2028-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07142369 on ClinicalTrials.gov