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Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop

NCT07139093 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2

Last updated 2026-04-03

No results posted yet for this study

Summary

The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and tACS on the behavioural and neural level. To test if the interface works in patients with DBS, the investigators record EEG during synchronized tACS-DBS in several patients. The investigators hypothesize that they can apply tACS at the desired phase-lags relative to DBS pulses and confirm this with EEG measurements of the DBS and tACS artifact.

Conditions

  • Deep Brain Stimulation
  • Parkinson's Disease (PD)

Interventions

DEVICE

DBS-coupled tACS

tACS will be applied in a phase-coupled manner, so that tACS and DBS are synchronized

Sponsors & Collaborators

  • University of Twente

    collaborator OTHER

  • University of Oxford

    collaborator OTHER

  • Universitätsklinikum Hamburg-Eppendorf

    lead OTHER

Principal Investigators

  • Bettina C. Schwab, PhD · UKE Hamburg

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
35 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-30
Primary Completion
2026-08-31
Completion
2026-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07139093 on ClinicalTrials.gov