68Ga-FAPI-46 PET/CT for the Prediction of Clinical Response to Neoadjuvant Therapy in Nasopharyngeal Carcinoma Patients
NCT07139054 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 31
Last updated 2025-08-24
Summary
The goal of this clinical trial is to learn about the prediction of clinical response to neoadjuvant therapy in nasopharyngeal carcinoma patients via 68Ga-FAPI-46 PET/CT. The main question it aims to answer is:
Can 68Ga-FAPI-46 PET/CT be used to evaluate the therapeutic response of neoadjuvant therapy for nasopharyngeal carcinoma? The researchers will compare the correlation between the parameters obtained after three 68Ga-FAPI-46 PET/CT scans and the treatment response after neoadjuvant and neoadjuvant combined with concurrent chemoradiotherapy.
Participants will:
Undergo three 68Ga-FAPI-46 PET/CT scans before starting treatment, after neoadjuvant therapy, and after concurrent chemoradiotherapy
Conditions
- Nasopharyngeal Cancer
Sponsors & Collaborators
-
The First Affiliated Hospital of Xiamen University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-31
- Primary Completion
- 2025-03-31
- Completion
- 2025-08-10
Countries
- China
Study Locations
More Related Trials
-
Neoadjuvant Chemotherapy Combined With Finotonlimab in the Treatment of Locally Advanced Hypopharyngeal Carcinoma
NCT07248956 ·Status: RECRUITING ·Phase: PHASE2
-
The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer
NCT06623487 ·Status: RECRUITING
-
40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma
NCT07328854 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Chemoradiotherapy Combined With Cetuximab in Nasopharyngeal Carcinoma
NCT01271439 ·Status: COMPLETED ·Phase: PHASE2
-
To Study the Feasibility and Quality of Life of Medial Group Retropharyngeal Node Sparing in Nasopharyngeal Carcinoma
NCT03346109 ·Status: UNKNOWN ·Phase: NA
-
A Multicenter Trial Evaluating the Efficacy of Nedaplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT01479504 ·Status: UNKNOWN ·Phase: PHASE3
-
Programmed Death-1 (PD-1) Antibody Combined With Chemoradiotherapy in High-risk Recurrent Nasopharyngeal Carcinoma
NCT03930498 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma
NCT06455410 ·Status: RECRUITING ·Phase: PHASE2
-
Reduced-dose Radiotherapy for Low-risk Stage III Patients With Nasopharyngeal Carcinoma
NCT03668730 ·Status: UNKNOWN ·Phase: PHASE2
-
Intensity-modulated Radiation Therapy Combined With Cisplatin or Nedaplatin Chemotherapy in Nasopharyngeal Carcinoma
NCT01265147 ·Status: UNKNOWN ·Phase: PHASE2
-
Combining PET/CT and EBV DNA to Evaluate the Hazard of Progression in the Follow-up of Locally Advanced NPC
NCT03601390 ·Status: COMPLETED
-
Adding PD-1 Inhibitor to Neoadjuvant and Adjuvant for NPC
NCT04557020 ·Status: RECRUITING ·Phase: PHASE3
-
Cisplatin-based and Carboplatin-based Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma
NCT03919552 ·Status: RECRUITING ·Phase: PHASE3
-
Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial
NCT05340491 ·Status: RECRUITING ·Phase: PHASE3
-
CTV Delineation Based Solely on Geometric Expansion From GTV in Nasopharyngeal Carcinoma
NCT06095154 ·Status: RECRUITING ·Phase: PHASE3
-
Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy
NCT07328841 ·Status: RECRUITING ·Phase: PHASE3
-
Concurrent Docetaxel Plus Cisplatin or Cisplatin Alone With IMRT in High Risk Nasopharyngeal Carcinoma
NCT02610556 ·Status: UNKNOWN ·Phase: PHASE2
-
To Evaluate the Efficacy and Feasibility of Modified Reduce-volume Target IMRT in the Treatment of Patients With Non-metastatic NPC
NCT04387266 ·Status: COMPLETED
-
Hypoxia Imaging -Guided Radiotherapy of Nasopharyngeal Carcinoma
NCT02089204 ·Status: UNKNOWN
-
Metronomic Capecitabine With or Without PD-1 Antibody as Adjuvant Therapy in High-risk Nasopharyngeal Carcinoma
NCT05342792 ·Status: RECRUITING ·Phase: PHASE3
-
Chemotherapy Plus Subsequent Loco-regional Radiotherapy Combined With Toripalimab in the De Novo Metastatic Nasopharyngeal Carcinoma
NCT04398056 ·Status: UNKNOWN ·Phase: PHASE2
-
The Value of 68Ga-grazytracer PET in Monitoring Responses to Immunotherapy of Advanced Soft Tissue Sarcomas
NCT06644287 ·Status: RECRUITING
-
Diagnosis of Adenoid Cystic Carcinoma on 68Ga-PSMA-617 PET-CT and Therapy With 177Lu-EB-PSMA-617
NCT04801264 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Adjuvant Treatment of Apatinib in Nasopharyngeal Carcinoma
NCT03612219 ·Status: UNKNOWN ·Phase: PHASE2
-
PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Salvage Locoregional Radiotherapy in De Novo Metastatic NPC
NCT07235319 ·Status: RECRUITING ·Phase: PHASE3